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Pigs Sus scrofa provide relevant biomedical models to dissect complex diseases due to their anatomical, genetic, and physiological similarities with humans. Aberrant DNA methylation has been linked to many of these diseases and is associated with gene expression; however, the functional similarities and differences between porcine and human DNA methylation patterns are largely unknown. DNA and RNA was isolated from eight tissue samples fat, heart, kidney, liver, lung, lymph node, muscle, and spleen from the adult female Duroc utilized for the pig genome sequencing project. RRBS reads were aligned using BSseeker2, and only sites with a minimum depth of 10 reads were used for methylation analysis. RNA-seq reads were aligned using Tophat, and expression analysis was performed using Cufflinks.

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When you think about careers that are intellectually stimulating, or good for the brain, STEM fields likely come to mind first: scientists, doctors, engineers. But what about a personal fitness trainer? Probably not a career that would top your list, but The New York Times has published a series of articles in recent months that look at research showing how exercise promotes brain health. From promoting the release of hormones that ease the symptoms of depression and anxiety to creating new brain cells in already developed adult brains, exercise has all kinds of positive impacts on the brain.
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Skip navigation! Story from Sex. By role-playing with your partner, you can abandon all inhibitions, get into character, and act out your most secret sexual fantasies. Did you have a crush on a hot professor in college, a former boss, or the cute barista from your local coffee shop?
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